Hemoglobin A1c

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Hemoglobin A1c (HbA1c) measures the amount of glucose bound to hemoglobin and indicates the control of glucose levels over 2 to 3 months. HbA1c is formed when glucose in the blood binds irreversibly to hemoglobin to form a stable complex.

Since the normal life span of erythrocytes is 90 to 120 days, HbA1c is eliminated only when red cells are replaced. HbA1c values are directly proportional to the concentration of glucose in the blood over the full life span of the red blood cells and are not subject to the fluctuations seen with daily blood glucose monitoring.