Prostate Specific Antigen (PSA)
Prostate specific antigen, total (PSA) is a protein produced by the cells of the prostate gland. A
PSA level in conjunction with a digital rectal exam is used to help detect prostate cancer in men 50
years of age and older. PSA levels are normally higher in older men compared with younger men,
even when there is no cancer. PSA is elevated in:
• Some healthy men.
• Some non-cancerous conditions, such as benign prostatic hyperplasia and prostatitis.
• 75% of men with prostate cancer.