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Thyroid Peroxidase Antibodies

Thyroid Peroxidase Antibodies

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The Thyroid Peroxidase Antibodies test measures the presence of antibodies against thyroid peroxidase, an enzyme essential for thyroid hormone production. High levels of these antibodies may indicate autoimmune thyroid conditions, such as Hashimoto's thyroiditis, where the immune system mistakenly attacks thyroid tissue. This test is vital for diagnosing and monitoring autoimmune thyroid disorders, which can lead to symptoms like fatigue, weight gain, and sensitivity to cold. Understanding your antibody levels can help you and your healthcare provider determine the best course of action for managing your thyroid health.

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About This Test

Reason to Check It

"Autoimmune thyroid disease is characterized by the occurrence of antibodies directed against the thyroid gland, referred to as autoantibodies. 

Individuals who have thyroid autoantibodies can progress to overt hypothyroidism at a rate of 3%-5% per year. A common thyroid autoantibody seen in people with hypothyroidism is called thyroid peroxidase antibody. If your thyroid peroxidase antibody is positive you may develop the signs and symptoms of hypothyroidism which includes weight gain, loss of energy and loss of sex drive." - Dr. Alan Hopkins

Test Preparation

  • No special preparation is required before your sample collection.


Please Note: We recommend overnight fasting and an early morning blood draw for all tests, even if no special preparation is required. Remember, it is OK to drink plenty of water. Drinking water helps hydrate you and makes it easier for the phlebotomist to obtain your blood sample.

Test Type and Method

Test Type:

  • Blood


Test Method:

  • In-person Blood Draw

Post-Test Notes

  • Once your specimen is collected, test results are typically processed and available within a few business days. Processing times may vary depending on the test. Your results will be delivered in a clear, easy-to-understand report. If any values fall outside the expected range, you may receive a follow-up call from an independent healthcare coordinator.

Lab Testing is Simple, Fast, and Convenient

Choose the Individual Test or Lab Panel that suits your health needs. You’ll receive your lab requisition within 24 hours. Visit any of the 3,000+ Quest Diagnostics centers using the button below. Once your sample is collected, your results will be securely delivered via email within 7–10 days.

View Quest Draw Locations

Lab Testing is Simple, Fast, and Convenient

Choose the Individual Test or Lab Panel that suits your health needs. You’ll receive your lab requisition within 24 hours. Visit any of the 3,000+ Quest Diagnostics centers using the button below. Once your sample is collected, your results will be securely delivered via email within 7–10 days.

View Quest Draw Locations