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Vitamin B12

Vitamin B12

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The Vitamin B12 test measures the level of vitamin B12 in your blood, an essential nutrient for nerve function, red blood cell production, and DNA synthesis. Deficiencies in B12 can lead to anemia, fatigue, and neurological issues. This test is particularly important for individuals following a vegetarian or vegan diet or those with absorption issues. Understanding your B12 levels can help guide dietary changes or supplementation to support overall health.

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About This Test

Reason to Check It

"Multiple, unrelated conditions may result in a person becoming vitamin B12 deficient, with varying degrees of vitamin B12 deficiency present in approximately 10-20% of individuals over the age of 60. 

People at risk for B12 deficiency include vegans or vegetarians who also don't eat dairy or eggs -- vitamin B12 is found only in animal products. Some individuals who develop a vitamin B12 deficiency have an underlying stomach or intestinal disorder that limits the absorption of vitamin B12 that is present in the food we eat.  The inability to absorb vitamin B12 may be due to the loss of intrinsic factor caused by atrophic gastritis.  Diseases and conditions such as celiac disease, gastric infections, gastric surgery and some medications may also affect absorption of vitamin B12."  - Dr. Alan Hopkins

Test Preparation

  • Fasting (Overnight) is recommended for 10-12 hours, but not required


Please Note: We recommend overnight fasting and an early morning blood draw for all tests, even if no special preparation is required. Remember, it is OK to drink plenty of water. Drinking water helps hydrate you and makes it easier for the phlebotomist to obtain your blood sample.

Test Type and Method

Test Type:

  • Blood


Test Method:

  • In-person Blood Draw

Post-Test Notes

  • Once your specimen is collected, test results are typically processed and available within a few business days. Processing times may vary depending on the test. Your results will be delivered in a clear, easy-to-understand report. If any values fall outside the expected range, you may receive a follow-up call from an independent healthcare coordinator.

Lab Testing is Simple, Fast, and Convenient

Choose the Individual Test or Lab Panel that suits your health needs. You’ll receive your lab requisition within 24 hours. Visit any of the 3,000+ Quest Diagnostics centers using the button below. Once your sample is collected, your results will be securely delivered via email within 7–10 days.

View Quest Draw Locations

Lab Testing is Simple, Fast, and Convenient

Choose the Individual Test or Lab Panel that suits your health needs. You’ll receive your lab requisition within 24 hours. Visit any of the 3,000+ Quest Diagnostics centers using the button below. Once your sample is collected, your results will be securely delivered via email within 7–10 days.

View Quest Draw Locations